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Rafiqi Lab - Eco-Evo-Devo

Rafiqi Lab - Eco-Evo-DevoRafiqi Lab - Eco-Evo-DevoRafiqi Lab - Eco-Evo-Devo

Ongoing work

 The lab investigates fundamental questions in evolution and development using two model organisms, C. floridanus and Anaceratagallia ribauti. Current projects focus on deciphering key developmental genetic pathways and gene regulatory networks, with special attention to how endosymbionts influence host gene expression, germline specification, and body plan patterning. By examining these interactions at molecular and cellular levels—including the evolution of specialized cell types such as bacteriocytes and related structures—the group aims to reveal how intimate host–symbiont relationships shape developmental processes.

   

More broadly, the research seeks to clarify the mechanisms underlying major evolutionary transitions and to integrate endosymbiotic theory into a modern synthesis–based evolutionary framework. Through studies of developmental integration between hosts and their symbionts, the lab explores how endosymbiosis can drive innovation, stabilize cooperative traits, and ultimately contribute to the evolution of complex multicellular organization. Use of state-of-the-art facilities and expertise for imaging, transgenesis, and genetic manipulation of insect embryos supports and accelerates these research efforts.

Current projects

Yaprak Piresi Kullanarak Endosimbiyontları Barındıran Hücrelerin Gelişiminin İncelenmesi

Yaprak Piresi Kullanarak Endosimbiyontları Barındıran Hücrelerin Gelişiminin İncelenmesi

Yaprak Piresi Kullanarak Endosimbiyontları Barındıran Hücrelerin Gelişiminin İncelenmesi

TÜBİTAK-1001

Learn more ınfo

Camponotus Karıncalarında BMP ve Hox Gen Düzenleyici Ağ Bağlantılarının Araştırılması

Yaprak Piresi Kullanarak Endosimbiyontları Barındıran Hücrelerin Gelişiminin İncelenmesi

Yaprak Piresi Kullanarak Endosimbiyontları Barındıran Hücrelerin Gelişiminin İncelenmesi

TÜBİTAK-1001

Learn more ınfo

State-of-art techniques

Animal Culture

Molecular Biology

Molecular Biology

Animal cultures in our lab

Molecular Biology

Molecular Biology

Molecular Biology

Cloning

Probe Synthesis

dsRNA Synthesis

RNA purification

Genome purification


Tissue Analysis

Molecular Biology

Tissue Analysis

Embryo fixation

In Situ Hybridization

Hybridization Chain Reaction

Immunohistochemistry

DAPI Staining

Microinjection

Molecular Biology

Tissue Analysis

Embryonic microinjection


Microscopy

Transcriptomics/ATACseq

Genome/RNA editing

Live Imaging

Phenotype Analysis

Genome/RNA editing

Transcriptomics/ATACseq

Genome/RNA editing

RNAi

CRISPR

Gain of function

Transcriptomics/ATACseq

Transcriptomics/ATACseq

Transcriptomics/ATACseq

Transcriptomic Sample Prep

ATAC-seq Sample Prep

CUT&RUN Sample Prep

Bioinformatic Analysis

Transcriptomics/ATACseq

Transcriptomics/ATACseq

De novo assembly

Expression dynamic 

Peak-calling

Mapping


Telif Hakkı © 2026 Rafiqi Lab - Eco Evo Devo - Tüm Hakları Saklıdır.

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